DIM is a plant-based supplement that supports hormone balance by detoxifying estrogen—making it a powerful ally for PMS, PCOS, and testosterone support. Found in cruciferous vegetables, the DIM supplement for hormone balance helps reduce estrogen dominance and improve hormonal ratios in both men and women.
At RevitalyzeMD in Knoxville, we frequently recommend the DIM supplement for hormone balance to patients struggling with estrogen dominance, PMS, or testosterone optimization.
DIM (Diindolylmethane) is a plant-based compound that supports estrogen detoxification, balances hormones in both men and women, and may indirectly support testosterone by reducing estrogen dominance. Found naturally in cruciferous vegetables, DIM helps shift estrogen metabolism from “bad” to “good” pathways. While it doesn’t increase total testosterone levels directly, it optimizes hormone ratios—especially helpful in PMS, PCOS, perimenopause, and TRT protocols.
Want to dive deeper? Watch our latest video on hormone-supportive supplements that promote balance, vitality, and graceful aging.
What Is DIM?
DIM—short for 3,3’-Diindolylmethane—is a natural compound formed when your body digests indole-3-carbinol (I3C), found in cruciferous vegetables like:
- Broccoli
- Cauliflower
- Brussels sprouts
- Kale
Known as “The Estrogen Detoxifier,” DIM supports healthy estrogen metabolism, which plays a critical role in hormonal balance for both men and women.
What Is a Medical-Grade Supplement?
Medical-grade (aka pharmaceutical-grade) supplements are held to a higher standard. Here’s what sets them apart:
✅ Third-party tested for purity, potency, and safety
✅ Clinically-dosed ingredients—no “label dressing”
✅ Research-backed formulations
✅ Enhanced bioavailability with liposomal delivery or chelated minerals
✅ Professional-only access—not sold in big-box stores
“You can take the right supplement—but if your body can’t absorb it, it’s a waste of money and time.”
At RevitalyzeMD, we only recommend supplements that support the clinical outcomes we’re targeting—and Designs for Health consistently delivers.
Why We Recommend Designs for Health
We’ve worked with many brands in functional medicine, but DFH stands out for their innovation, transparency, and integrity.
Here’s why we rely on them:
- Over 30 years of leadership in functional & integrative medicine
- Clean ingredients with no artificial dyes, additives, or preservatives
- Exceptional education and research support for providers
Custom protocols for hormones, GI repair, detox, aging, and more
Our Favorite DFH Products for Wellness Optimization
- Hi-PO – inflammation, brain + cardiovascular support
- Collagen Powder – skin, joints, gut lining
- DIM-Evail, FemGuard+Balance, Adrenotone – for hormone support
- NAC – detox, liver function, oxidative stress
- DHEA – hormone and energy support
- Lithium Synergy – immune and skin function
How We Use Designs for Health in Clinical Practice
Supplements at RevitalyzeMD aren’t generic. They’re personalized and protocol-based to support hormone balance, gut healing, recovery, and vitality.
We use Designs for Health across our core wellness services:
- Menopause & Perimenopause protocols
- Testosterone Optimization & Andropause support
- Gut repair plans after food sensitivity testing
- Post-procedure recovery (microneedling, threads, lasers)
- Peptide and hormone stacking strategies

Dr. Durst’s clinical Perspective
“We treat the root cause and support the system—supplements are an essential part of that.”
— Dr. Debra Durst, Double Board-Certified in Functional & Regenerative Medicine
frequently asked questions
What’s the difference between medical-grade and store-bought supplements?
Medical-grade supplements are third-party tested for potency and purity, use clinically backed doses, and have enhanced bioavailability. Over-the-counter (OTC) products often contain fillers, underdosed ingredients, or unverified formulations.
Do I need a prescription to order from Designs for Health?
You don’t need a prescription, but you do need practitioner access. RevitalyzeMD patients can shop directly through our DFH practitioner store for exclusive, high-quality formulations.
Can supplements really improve hormone balance or gut health?
Absolutely. When paired with the right clinical testing and protocols, supplements can support detox, hormone metabolism, gut lining repair, inflammation, energy production, and more. We customize every regimen for your unique biochemistry.
Are these supplements safe to take long term?
Yes—because they’re free from unnecessary fillers, preservatives, and synthetic dyes. Each product is formulated to be safe and effective, with many designed for long-term foundational support.
How do I know which supplements are right for me?
The best way is to book a wellness consult at RevitalyzeMD. We’ll assess your labs, symptoms, and goals, then recommend a supplement protocol that works in synergy with your hormones, peptides, or lifestyle.
Ready to Start Your Custom Supplement Plan in Knoxville?
You don’t need a shelf full of random vitamins—you need a strategic, science-backed supplement protocol that works. At RevitalyzeMD, we trust Designs for Health because quality isn’t a luxury—it’s the standard.
Why Choose Medical-Grade with RevitalyzeMD?
✅ Pharmaceutical-grade quality backed by third-party testing
✅ Clinically effective, bioavailable ingredients
✅ Personalized supplement plans based on labs, symptoms, and outcomes
Whether you’re supporting hormones, gut health, inflammation, or recovery, your body deserves the best.
Book a wellness consultation to build your custom protocol with our team. If you’re looking for medical-grade supplements in Knoxville, our team can guide you to the right protocol.